Split Hospital First in Croatia to Use Blue Light for Bladder Cancer Diagnosis

The University Hospital Centre Split (KBC Split) has become the first medical institution in Croatia to introduce blue light cystoscopy — an advanced diagnostic method that allows doctors to detect bladder cancer earlier and more precisely than with standard techniques.

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At the Clinic for Urology, urologists led by Dr Mirnes Selimović and Dr Žana Saratlija used a special diagnostic agent containing hexaminolevulinate and examined patients’ bladders under blue light, which makes suspicious areas stand out clearly due to fluorescence.

Tumour cells absorb the agent more than healthy tissue, so under blue light they glow bright pink or purple, increasing the chances of spotting early-stage or flat lesions that white light cystoscopy can miss.

The technique is not a treatment but a diagnostic tool used before procedures like transurethral resection of bladder tumours (TURBT) or in follow-up exams for patients previously diagnosed with bladder cancer. Hospital officials say this step aligns the Clinic for Urology with leading international standards, modernises urological care and is expected to help detect disease earlier and improve the quality and safety of patient care.